T cell receptor-independent immunosuppression induced by dexamethasone in murine T helper cells.
نویسندگان
چکیده
منابع مشابه
T cell receptor-independent immunosuppression induced by dexamethasone in murine T helper cells.
The immune and inflammatory responses are largely inhibited by glucocorticosteroids. In thymocytes, for example, glucocorticosteroids cause apoptosis, whereas they suppress the activity of phospholipase A2 and the production of eicosanoids in tissues actively engaged in inflammation. The immunosuppressive action of dexamethasone (DEX) was studied in vitro by employing a model cell system, namel...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1992
ISSN: 0021-9738
DOI: 10.1172/jci115620